【摘要】 类志贺邻单胞菌O17血清型与宋内氏痢疾志贺氏菌的脂多糖结构一致,类志贺邻单胞菌7-63-5株属于O17血清型。实验中通过对该菌株培养特性、生化特征、免疫学特性的研究,证明其完全符合类志贺邻单胞菌特性。多糖的研究证明,类志贺邻单胞菌7-63-5株的O-特异性多糖无论从化学结构,还是免疫学特性上,都与宋内氏I相菌的一致。因此,类志贺邻单胞菌7-63-5株可以用以研究宋内氏痢疾多糖蛋白质结合疫苗。更多还原

【Abstract】 The lipopolysaccharides(LPS) of P.shigelloides sera-type O17 is identical to that of Shigella sonnei.P.shigelloides strain 7-63-5 belongs to sera-type O17.In this study,the results of morphology,biochemical characteristics and serology of this strain are all in conformation with those of P.shigelloides strain.Studies on polysacchrides also demonstrate that P.shigelloides strain 7-63-5 have a structure and immunological properties in common with the O-specific polysaccharides of S.sonnei form I.As a conclusion,P.shigelloides strain 7-63-5 could be used as a production strain to develop conjugate vaccine of S.sonnei.更多还原