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功能性消化不良患者心理因素和自主神经功能的研究

Psychologic Factors and Autonomic Nervous Activity in Patients with Functional Dyspepsia

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【作者】 张晓光胡品津王启仪林金坤

【Author】 ZHANG Xiaoguang, HU Pinjin, WANG Qiyi, LIN Jinkun. Department of Gastroenterology, Guangdong Provincial People’s Hospital, Guangzhou (510080)

【机构】 广东省人民医院消化内科中山大学附属第一医院消化内科中山大学附属第一医院消化内科 510080510080

【摘要】 心理因素可能与功能性消化不良(FD)的发病有关,但FD患者的自主神经功能状态及其与心理因素之间的关系尚不明确。目的:探讨心理因素、自主神经功能以及FD之间的关系。方法:以症状自评量表-90(SCL-90)和24h心率变异性(HRV)分析分别评定22例FD患者和20名健康对照者的心理状态和自主神经功能。结果:FD患者大多数心理因子分均较健康对照者显著升高(P<0.05),而自主神经功能与健康对照者相比无显著差异(P>0.05)。有躯体化障碍或焦虑的FD患者,其自主神经功能状态与无躯体化障碍或焦虑者相比有显著差异(P<0.05)。结论:心理障碍与FD的发生密切相关,自主神经功能障碍可能是两者间的中间环节。

【Abstract】 Background: Psychologic factors may contribute to the occurrence of functional dyspepsia (FD), but autonomic nervous activity and its relationship with psychologic status in FD patients have not been defined. Aims: To investigate the relationship between psychologic status, autonomic nervous activity and FD. Methods: Symptom checklist-90 (SCL-90) and 24-hour heart rate variability (HRV) analysis were used to evaluate the psychologic status and autonomic nervous activity in 22 FD patients and 20 healthy controls. Results: The scores of most psychologic factors among FD patients were markedly higher than those among the healthy controls (P<0.05). However, no significant statistical difference in autonomic nervous activity was found between the two groups (P>0.05). There had been significant statistical difference in autonomic nervous activity between FD patients with and without somatoform disorder or anxiety (P<0.05). Conclusions: Psychologic distress is closely related with FD, and autonomic nervous dysfunction may be the intermedium between them.

【关键词】 消化不良心理学自主神经系统
【Key words】 DyspepsiaStomachPsychologyAutonomic Nervous System
  • 【文献出处】 胃肠病学 ,Chinese Journal of Gastroenterology , 编辑部邮箱 ,2006年05期
  • 【分类号】R57
  • 【被引频次】114
  • 【下载频次】400
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