【摘要】 研究了米托蒽醌在多壁碳纳米管修饰电极上的伏安行为,发现多壁碳纳米管能显著提高米托蒽醌的氧化峰电流.通过选择和优化各项参数,建立了一种直接测定米托蒽醌的电分析方法.该方法的线性范围为2.8×10-8~1.1×10-6mol.L-1;开路富集4 min后,检出限为5.6×10-9mol.L-1;平行测定1.0×10-7mol.L-1米托蒽醌10次的相对标准偏差(RSD)为4.6%.该方法被应用于米托蒽醌注射液中米托蒽醌的含量测定,结果满意.更多还原

【Abstract】 The voltammetric behavior of mitoxantrone on the MWNT modified electrode was investigated.It is found that MWNT film significantly enhances the oxidation peak current of mitoxantrone.All the experimental parameters were optimized,and a sensitive electrochemical method was developed for the determination of mitoxantrone.The oxidation peak current is linear with the concentration of mitoxantrone from 2.8×10^-8 to 1.1×10^-6 mol·L^-1.The detection limit is about 5.6×10^-9 mol·L^-1 for 4 min accumulation.The relative standard deviation（n=10） was 4.6% for 1.0×10^-7 mol·L^-1mitoxantrone.This method can be successfully used in the determination of content of mitoxantrone in mitoxantrone injections.更多还原