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β-磷酸三钙/硅酸钙复合生物陶瓷的制备及性能研究
Fabrication and Characterization of β-Ca3(PO4)2/CaSiO3 Composite Bioceramics
【摘要】 以β-磷酸三钙/硅酸钙(β-TCP/CS)纳米复合粉体为原料,制备了质量比为50∶50的β-TCP/CS复合生物陶瓷.研究表明,1150℃烧结5h得到的样品强度最好,其致密度>96%,晶粒尺寸约120nm,强度达126MPa、同人体致密骨相当;复合陶瓷在模拟体液中浸泡1天表面就全部被类骨羟基磷灰石层覆盖住,28天的降解率达10.1%,具有良好的生物活性和降解性.研究结果显示β-TCP/CS复合生物陶瓷有望作为强度较好的可降解生物活性硬组织修复材料.
【Abstract】 Theβ-Ca3(PO4)2/CaSiO3 (β-TCP/CS) composite bioceramics with weight ratio of 50:50 were fabricated by using theβ-TCP/CS nano-composite powders.Theβ-TCP/CS composite bioceramics with>96% relative density and 120nm grain size were obtained after sintering at 1150℃for 5h.The bending strength of the samples reached about 126MPa,which was similar to those of the human cortical bone.After soaking in simulated body fluid for 1 day,the samples were completely covered wity hydroxyapatite layers.The degradability of the samples reached 10.1% within 28 days in vitro.The results suggest excellent in vitro bioactivity and degradability of theβ-TCP/CS composite bioceramics.Therefore,theseβ-TCP/CS composite bioceramics may be potential candidates as good mechanical strength,bioactive and degradable biomaterials for hard tissue repair applications.
【Key words】 β-trualcium phosphate/calcium silicate; composite bioceramics; mechanical strength; bioactivity; degradability;
- 【文献出处】 无机材料学报 ,Journal of Inorganic Materials , 编辑部邮箱 ,2006年06期
- 【分类号】R318.08
- 【被引频次】23
- 【下载频次】554