节点文献

β-磷酸三钙/硅酸钙复合生物陶瓷的制备及性能研究

Fabrication and Characterization of β-Ca3(PO42/CaSiO3 Composite Bioceramics

  • 推荐 CAJ下载
  • PDF下载
  • 不支持迅雷等下载工具,请取消加速工具后下载。

【作者】 林开利常江卢建熙高建华曾毅

【Author】 LIN Kai-Li CHANG Jiang LU Jian-Xi GAO Jian-Hua ZENG Yi (Shanghai Institute of Ceramics,Chinese Academy of Sciences,Shanghai 200050,China)

【机构】 中国科学院上海硅酸盐研究所中国科学院上海硅酸盐研究所 上海 200050上海 200050

【摘要】 以β-磷酸三钙/硅酸钙(β-TCP/CS)纳米复合粉体为原料,制备了质量比为50∶50的β-TCP/CS复合生物陶瓷.研究表明,1150℃烧结5h得到的样品强度最好,其致密度>96%,晶粒尺寸约120nm,强度达126MPa、同人体致密骨相当;复合陶瓷在模拟体液中浸泡1天表面就全部被类骨羟基磷灰石层覆盖住,28天的降解率达10.1%,具有良好的生物活性和降解性.研究结果显示β-TCP/CS复合生物陶瓷有望作为强度较好的可降解生物活性硬组织修复材料.

【Abstract】 Theβ-Ca3(PO42/CaSiO3 (β-TCP/CS) composite bioceramics with weight ratio of 50:50 were fabricated by using theβ-TCP/CS nano-composite powders.Theβ-TCP/CS composite bioceramics with>96% relative density and 120nm grain size were obtained after sintering at 1150℃for 5h.The bending strength of the samples reached about 126MPa,which was similar to those of the human cortical bone.After soaking in simulated body fluid for 1 day,the samples were completely covered wity hydroxyapatite layers.The degradability of the samples reached 10.1% within 28 days in vitro.The results suggest excellent in vitro bioactivity and degradability of theβ-TCP/CS composite bioceramics.Therefore,theseβ-TCP/CS composite bioceramics may be potential candidates as good mechanical strength,bioactive and degradable biomaterials for hard tissue repair applications.

【基金】 上海市科委资助项目(0352nm119、05DJ14005);国家973资助项目(2005CB522704)
  • 【文献出处】 无机材料学报 ,Journal of Inorganic Materials , 编辑部邮箱 ,2006年06期
  • 【分类号】R318.08
  • 【被引频次】23
  • 【下载频次】554
节点文献中: 

本文链接的文献网络图示:

本文的引文网络