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训练与补脾益肾中药对雄性大鼠睾酮生物合成酶活性的影响

Effects of BUPIYSHEN Traditional Chinese Herbs on Enzymes Activity Involuing Testosteron Biosynthesis in Male Rats of Training Model

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【摘要】 运动性血睾酮降低是影响运动员运动能力和运动后恢复的重要因素之一。在我们的研究中,SD大鼠在5周的高强度大运动量训练后,血睾酮和睾丸内睾酮均明显降低(p<0.01),睾酮生物合成过程的3β-羟类固醇脱氢酶(3β-HSD)和限速酶--胆固醇侧链裂解酶(P450scc)的活性均明显降低(p<0.01),而在训练中同时灌服补脾益肾中药的大鼠在5周训练后血睾酮与胆固醇侧链裂解酶活性与安静对照组相比无明显差异,说明了我们使用的中药有益于运动训练中下丘脑-垂体-性腺轴(HPG)功能的稳定,对运动造成的血睾酮持续低水平有预防与改善作用。

【Abstract】 Foe the athletes′ performance and recovery,The exercise induced lower serum testosterone is one important impact factor.In our investigation protocol,after 5 weeks intensive training load and high training volume,testosterone content of SD rats were in serum and testis were decreased(p<0.01),enzyme activity of 3β-HSD and P450scc also decreased significantly(p<0.01),they involved in the biosynthesis of testosterone and P450scc is the rate limited enzyme.but the serum testosterone content and P450scc activity of rats which were given BUPI YISHEN Traditional Chinese herbs through stomach during 5 weeks training have no obvious different compared with normal control group,indicating that the BUPI YISHEN Traditional Chinese herbs is beneficial for the HPG axe function,it is effect in preventing exercise induced lower serum testosterone

  • 【文献出处】 体育与科学 ,Journal of Sports and Science , 编辑部邮箱 ,2006年05期
  • 【分类号】G804
  • 【被引频次】4
  • 【下载频次】191
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