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卵泡刺激素、黄体生成素对卵母细胞成熟的调节作用
Role of follicle stimulating hormone and luteinizing hormone in oocyte maturation
【摘要】 遵循两细胞两促性腺激素的理论,卵泡刺激素(FSH)、黄体生成素(LH)对于卵泡成熟和卵巢性腺类固醇的产生都是必需的。在体内FSH启动卵泡生长,LH促进卵母细胞成熟。FSH及LH的应用显著缩短了卵母细胞体外成熟(IVM)的时间,提高卵母细胞成熟及发育的潜能,提高妊娠率。因此揭示卵母细胞核质成熟的影响因素,对提高IVM卵母细胞的质量至关重要。
【Abstract】 Both follicle stimulating hormone(FSH) and luteinizing hormone(LH) are necessary for ovarian follicular maturation and the production of ovarian steroids.FSH promotes follicular growth,and LH stimulates follicular maturation in vivo.The use of FSH and LH has not only shortened the duration of oocyte maturation in vitro,but also improved its development potential.Both of FSH and LH simulate follicular growth in vitro and have important effects on its quality.So it is important to reveal all the related factors for improving the quality of in vitro maturation oocyte.
- 【文献出处】 生殖医学杂志 ,Journal of Reproductive Medicine , 编辑部邮箱 ,2006年05期
- 【分类号】R714
- 【被引频次】7
- 【下载频次】496