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痛风定冲剂抗炎镇痛作用的实验研究

Experimental Studies on Anti-inflammation and Analgesic Action of TongFengDing Granules

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【作者】 张玉祥王希黄少斌

【Author】 ZHANG Yu-xiang~1,WANG Xi~1,HUANG Shao-bin~2 (1.Guangdong Vocational College of Chemical Engineering & Pharmaceutics,Guangzhou 510520,China;(2.Guangzhou) Huacheng Pharmaceutical Factory,Guangzhou,510555,China)

【机构】 广东化工制药职业技术学院广州花城制药厂 广东广州510520广东广州510520广东广州510555

【摘要】 目的研究痛风定冲剂的抗炎镇痛作用。方法通过小鼠耳廓肿胀、大鼠足跖肿胀、大鼠踝关节肿胀等实验观察其抗炎作用;通过热板法和醋酸扭体法观察其镇痛作用。结果痛风定冲剂能显著抑制二甲苯所致小鼠耳廓肿胀,角叉菜胶致大鼠足跖肿胀,尿酸钠致大鼠踝关节肿胀;提高热板法疼痛模型小鼠痛阈值,抑制醋酸所致小鼠扭体痛反应。结论痛风定冲剂具有显著的抗炎、镇痛作用。

【Abstract】 Objective To investigate the anti-inflammation and analgesic action of TongFengDing Granules.Methods Observe the anti-inflammation by mouse auricular swelling,rat metatarsal swelling and rat pedal swelling experiments;observe the analgesic action by micehot-board and acetic-acid-induced twisting experiments.Results TongFengDing Granules had obvious inhibitory effect on mouse auricular swelling induced by sodium wrate,metatarsal swelling induced by pelvalia siliguosa gelatine and pedal swelling induced by improving the hot paw threshold,inhibit twisting reaction induced by aceticacid in mice.Conclusion TongFengDing Granules have obvious antiinflammation and analgesic actions.

【关键词】 痛风定冲剂抗炎镇痛
【Key words】 Tong Feng Ding GranulesAnti-inflammationAnalgesic action
  • 【文献出处】 时珍国医国药 ,LiShiZhen Medicine and Materia Medica Research , 编辑部邮箱 ,2006年12期
  • 【分类号】R285.5
  • 【被引频次】6
  • 【下载频次】190
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