【摘要】 目的探讨血浆中脑钠肽(BNP)浓度对判断心力衰竭严重程度及其预后的价值。方法选取60例心力衰竭住院患者,按纽约心脏协会(NYHA)分级标准分为Ⅰ~Ⅳ级,均检测BNP,同时收集Ⅲ级、Ⅳ级患者30 d内死亡者及存活者例数。结果Ⅰ级、Ⅱ级、Ⅲ级、Ⅳ级各级患者BNP逐渐升高(P<0.001);且在Ⅲ级、Ⅳ级患者中,30 d内死亡者相对于存活者BNP值更低(P<0.001)。结论BNP对心力衰竭的危险程度及终末期心衰短期预后具有重要的评估价值。更多还原

【Abstract】 Objective To investigate the value of BNP in diagnosis of heart failure level and its prognosis.Methods This study consisted of 60 patients with heart failure in New York Heart Association functional class Ⅰ～Ⅳ,and had BNP measured.Within 30 day,survivors and died patients in class Ⅲ～Ⅳ were enrolled.Results Levels of BNP gradually elevated in patients of class Ⅰ～Ⅳ(P<(0.001)),and plasma levels lowered in the died patients in class Ⅲ～Ⅳ within 30 day(P<0.001).Conclusion Plasma BNP has an important evaluation of heart failure and lower levels of BNP predict short-term mortality in the end-stage heart failure.更多还原