【摘要】 目的研究糖尿病视网膜病变与血浆同型半胱氨酸水平的关系。方法随机选择2型糖尿病患者120例,按有无视网膜病变分为3组：糖尿病无视网膜病变组(NDR)、背景型糖尿病视网膜病变组(BDR)和增殖型糖尿病视网膜病变组(PDR),检测3组患者的血浆同型半胱氨酸水平。结果BDR组与PDR组患者的Hcy水平明显高于NDR组(P＜0．01),PDR组的Hcy水平明显高于BDR组(P＜0．05),差异均有显著性意义(P＜0．05)。结论高同型丰胱氨酸血症不仅促进糖尿病视网膜病变的发生,而且与糖尿病视网膜病变的严重程度有关。更多还原

【Abstract】 Objective To evaluate the relationship between diabetic retinopathy and plasma hyperhomocysteinemia. Methods 120 type 2 diabetic patients were enrolled,the 120 patients were assigned to three groups:NDR,BDR and PDR. All patients’ plasma homocysteine were measured.Results The plasma homocysteine of BDR and PDR were significantly higher than NDR,the plasma homocysteine of PDR was significantly higher than BDR.Conclusion Hyperhomocysteinemia can cause diabetic retinopathy,hyperhomocysteinemia is related with the severities’order of diabetic retinophthy.更多还原