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早期应用尿激酶静脉溶栓治疗急性脑梗死的疗效观察

The Curative Observation of Intravenous Thrombolysis for Early Acute Cerebral Infarction with Urikinace

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【作者】 刘可权胡文忠吴趋王晓鸣陈穗

【Author】 LIU Ke-quan,HU Wen-zhong,WU Qu,et al.The Hospital of Luo-cun,Nanhai region,Foshan 528226,China

【机构】 广东省佛山市南海区罗村医院广东省佛山市南海区罗村医院

【摘要】 目的探讨早期应用尿激酶静脉溶栓治疗急性脑梗死的疗效及安全性。方法随机将69例急性脑梗死患者分为溶栓治疗组与常规治疗组,两组同时给予降颅压,脑细胞营养保护剂,钙离子拮抗剂等治疗。前者在此基础上应用尿激酶100万U加入0.9%氯化钠溶液100ml静滴,30min内滴完。在治疗前后对临床疗效(神经功能缺损评分,日常生活能力状态评分)、并发症、CT等方面进行比较分析。结果治疗组与对照组比较疗效差异有显著性意义(P<0.05)。结论早期应用尿激酶静脉溶栓治疗急性脑梗死疗效明显,是一种有效,安全的治疗方法。

【Abstract】 Objective To study the clinical efficacy and reliability of urikinace in the treatment of early acute cerebral infarctions.Methods 69 patients were randomly divided into two groups:thrombolysis group and control group.For thrombolysis group,100 thousand unit urikinace added into 100ml sodium chloride was injected by drip within 30 minutes.Both groups were also treated with lowing cephalic pressure,brain cell protection cesium antagonist etc.the curative effects and complications have been observed.Results The effective rate in experimental group was higher than that in the control group.Statistical difference was found between the two groups.There was no difference in the incidence of complications between two groups.Conclusion Urikinace could result in good clinical effects and safety in the treatment of early acute cerebral infarctions.

  • 【文献出处】 实用心脑肺血管病杂志 ,Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease , 编辑部邮箱 ,2006年03期
  • 【分类号】R743.3
  • 【下载频次】44
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