【摘要】 目的探讨血液透析并滤过(HDF)在小儿急性肾衰竭(ARF)的应用。方法应用Branc Dialog双泵透析机对因各种原因致ARF需行血液净化治疗的11例患儿进行19例次HDF和21例次血液透析(HD)。HDF及HD前后分别测血BUN、Cr、UA、β2-微球蛋白(β2-MG),观察心率、血压、体温等变化。结果HDF与HD相比,血BUN、Cr、UA、β2-MG下降率均增高,经统计学处理P<0.01,低血压发生率低,HDF无低血压发生,HD为5/21例次。但失衡综合征发生率HD无,HDF 3/19例次。结论HDF较HD透析充分,特别是对血β2-MG清除率高,血流动力学稳定,但要防止失衡综合征的发生。更多还原

【Abstract】 Objective To discuss the application of the hemodialysis and filtration（HDF） in children with acute renal failure（ARF）.Methods By Branc Dialog hemodialysis machine of double-pump,HDF for 19 times and hemodialysis（HD） for 21 times were given to the children with ARF.The serum blood urea nitrogen（BUN）,creatinine（Cr）,uric acid（UA）,β₂ microglobulin（β₂-MG） and the rate of the heart,blood pressure,temperature were observed before and after HD and HDF.Results The clearance rates of BUN,Cr,UA,（β₂-）MG of HDF were markedly higher than those of HD（P<0.01）.The incidence rate of hypotension in HDF was lower,none in HDF,5/21 times in HD.As to the unbalanced syndrome,none in HD,3/19 in HDF.Conclusions Compared with HD,HDF is more efficient.The clearance rate of low-molecular-weight protein（such as serum β₂-MG） is higher than that of HD;blood pressure is steady,but the unbalanced syndrome shall be prevented.更多还原