【摘要】 目的评价12导联同步体表心电图(12 ECGs)T波振幅在儿童扩张型心肌病(DCM)诊断和治疗中的价值。方法DCM患儿27例为研究组。男14例,女13例;年龄3个月~14岁,平均5.37岁。随机匹配健康儿童27例为对照组。受检对象描记12 ECGs,测量波形清晰12导联T波振幅。其中10例DCM患儿经氢氯噻嗪、依那普利、美托洛尔、螺内酯等综合治疗后随访5~39 d,平均19.67 d。结果研究组较对照组T波振幅在Ⅰ、Ⅱ、aVR、aVL、aVF、V4、V5、V6导联明显降低(P均<0.05),Ⅲ、V2、V3导联稍降低(P均>0.05),V1导联T波振幅增高(P<0.05)。DCM患儿治疗后较治疗前T波振幅在Ⅲ、aVF导联明显增高(P<0.05),Ⅱ、aVR、aVF、V5导联稍增高(P均>0.05),Ⅰa、VL、V1~V4、V6导联稍降低(P均>0.05)。结论动态观察12 ECGs的T波振幅,对儿童DCM诊断和评价疗效具有客观指导价值。更多还原

【Abstract】 Objective To evaluate the clinical diagnosis and therapeutic effect of 12-lead electrocardiographic T-wave amplitude in children with dilated cardiomyopathy（DCM）.Methods 12-lead electrocardiograms（12 ECGs） were taken from 27 cases in children with DCM（research group） aged from 3 months to 14 years old （mean 5.37 years）,27 healthy children（control group）,and 10 cases which treated with dihydrochlorothiazede enalapril spironolactone metoprolol and followed up from 5 to 39 days（mean 19.67 days）.The T-wave amplitude was tested in the clear 12 ECGs.Results Compared with control group on T-wave amplitude,Ⅰ,Ⅱ,aVR,aVL,aVF,V₄,V₅,V₆ leads obviously decreased（P<0.05）;Ⅲ,V₂,V₃ leads slightly decreased（P>0.05）;V₁ lead increased（P<0.05）.Compared with the group before treating on T-wave amplitude,Ⅲ,aVF leads obviously increased（P<0.05）;Ⅱ,aVR,aVF,V₅ leads slightly increased（P>0.05）;Ⅰ,aVL,V₁-V₄,V₆ lead slightly decreased（P>0.05）.Conclusion 12-lead electrocardiographic T-wave amplitude has the objective and leading value to clinical diagnosis and treatment in children with DCM.更多还原