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米索前列醇预防产后出血的疗效观察

The clinical effect of Misoprostal in preventing postpartum hemorrhage

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【作者】 谢家凤邓小梅曾晓岚

【Author】 XIE Jia-feng,DENG Xiao-mei,ZENG Xiao-lan.Department of Obstetrics ,Nanhai County People’s Hospital , Foshan Guangdong 528000,China.

【机构】 佛山市南海区人民医院产科佛山市南海区人民医院产科 广东佛山528000广东佛山528000

【摘要】 目的探讨米索前列醇预防产后出血的临床效果。方法将86例存在产后出血危险性的产妇随机分成两组,观察组于直肠给予米索前列醇600μg,对照组于分娩后立即肌内注射催产素20U,对两组的出血量、产后出血发生率及不良反应进行观察比较。结果观察组产妇产后2h出血量为(267.5±53.5)ml,对照组为(423.6±37.8)ml,两组相比存在非常显著性差异(P<0.01)。观察组产后出血率为2.3%,对照组为20.9%,两组比较有非常显著性差异(P<0.01)。结论米索前列醇直肠用药能较好地预防产后出血,且用药方便。

【Abstract】 Objective To investigate the effect of Misoprostal in preventing postpartum hemorrhage .Methods 86 patients that had the risk of postpartum hemorrhage were randomly divided into two groups . The case group was given 600μg Misoprostal;The control group was given 20U oxytocin after labor . The hemorrhage amount,the incidence of postpartum hemorrhage and side effects in the two groups were contrasted . Results The hemorrhage amount of the case group and the control group were(267 . 5 ± 53.5)ml and (423.6 ± 37.8)ml respectively; The hemorrhage rate of the case group and the control group were 2.3% and 20.9%,The difference was significant( P < 0 .01)between them.Conclusion The application of Misoprostal through rectum is effective and simple to prevent postpartum hemorrhage.

【关键词】 米索前列醇产后出血预防
【Key words】 MisoprostalPostpartum hemorrhagePrevention
  • 【文献出处】 临床和实验医学杂志 ,Journal of Clinical and Experimental Medicine , 编辑部邮箱 ,2006年09期
  • 【分类号】R714.4
  • 【被引频次】5
  • 【下载频次】14
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