【摘要】 目的:研究运用自体喙突移植重建髁突的可行性及其整复效果。方法:选取12只成年雄性山羊,手术截除右侧髁突与关节盘,取同侧喙突以L型钛板固定在下颌升支。分别在术后第4、12、24周各处死4只动物。通过大体观察、三维CT分析和组织学检查等方法评价自体喙突移植后的形态学和组织学变化。结果:所有动物术后咬合基本正常。术后4周可见喙突再生,术后24周时自体喙突形态基本接近正常髁突。新生髁突表面有较厚的致密纤维结缔组织覆盖,其下方的组织结构类似正常髁突表面的关节软骨。结论:自体喙突移植可以重建一个形态和功能都基本接近正常的髁突,因此这种技术可以作为一种整复TMJ缺损的新方法。更多还原

【Abstract】 Objective:To evaluate the applicability of reconstruction of mandibular condyle by autogenous coronoid process in goats.Methods:12 adult male goats were used. Condyles and articular discs on right side were extirpated, and the coronoid process on the same side was removed and fixed to the mandibular ramus by a L-shape miniplate to reconstruct the condyle.Those on the left side were kept intact as controls. Gross examination and CT scanning images were taken at various intervals. 4 animals selected at random were sacrificed respectively at 4, 12 and 24 weeks postoperatively, and the newly formed condyles were harvested and processed for histological examination.Results: Malocclusion was found in none of the animals after operation. The resected coronoid process regenerated 4 weeks after operation. The shape and appearance of the grafted coronoid process was similar to that of the original condyle at 24 weeks after operation. A layer of dense fibrous connective tissue was observed covering the surface of the neocondyles, beneath which was articular cartilage similar to the original.Conclusion: A neocondyle with functional shape can be created by grafted coronoid process.更多还原