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脑卒中患者血浆总同型半胱氨酸的测定及其临床意义
Determination of plasma total homocysteine in patients with cerebral apoplexy and its clinical significance
【摘要】 目的:探讨血浆总同型半胱氨酸与脑卒中的关系及其临床意义。方法::选择脑卒中患者120例作为脑卒中组,并选择120例性别、年龄和种族等与脑卒中组相匹配的无脑卒中者作为对照组,采用荧光偏振免疫检测方法测定血浆总同型半胱氨酸。结果:脑卒中组血浆总同型半胱氨酸水平(17.82±4.21μmol/L)显著高于对照组(13.82±3.59μmol/L),P<0.05。结论:血浆总同型半胱氨酸水平升高与脑卒中的发生密切相关,控制血浆总同型半胱氨酸水平对预防脑卒中的发生有重要意义。
【Abstract】 Objective: To study the relationship between cerebral apoplexy and plasma level of total homocysteine (tHcy) and its clinical significance.Methods: One hundred and twenty patients with cerebral apoplexy were included as the case group in this study while 120 subjects without cerebral apoplexy matched with the case group on the characteristics of sex, age, and race were selected as control group. Plasma level of total tHcy was measured by fluorescence polarization immunoassay.Results: The plasma level of tHcy in the case group was significantly higher than that of the control group 〔(17.82±4.21) mmol/L vs (13.82±3.59) mmol/L, [WTBX]P<0.05〕.Conclusion: Increased plasma level of tHcy is closely correlated with the occurrence of cerebral apoplexy. Control of plasma level of tHcy plays an important role in prevention of cerebral apoplexy.
【Key words】 homocysteine; cerebral apoplexy; fluorescence polarization immunoassay;
- 【文献出处】 上海医药 ,Shanghai Medical & Pharmaceutical Journal , 编辑部邮箱 ,2006年06期
- 【分类号】R743.3
- 【被引频次】1
- 【下载频次】56