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芦荟凝胶对放射性皮炎愈合过程中肉芽组织及创面愈合率的影响

Efficacy of aloe gel for wound healing rate and the granulation tissue rate in the dermatitis vesicular reaction caused by radiation in rats

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【作者】 卢金利; 刘小平; 杨芳; 李明众;

【Author】 LU Jin-li~1,LIU Xiao-ping~1,YANG Fang~2,LI Ming-zhong~1 Department of Radiation Oncology, First Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710061 China

【机构】 西安交通大学第一医院肿瘤放疗科; 西安交通大学西区图书馆; 西安交通大学第一医院肿瘤放疗科 陕西西安710061; 陕西西安710061;

【摘要】 目的:观察芦荟凝胶对大鼠放射性皮炎愈合过程中创面愈合率及肉芽组织的影响。方法:首先建立SD大鼠裸露背部10%Ⅱ度放射性皮炎模型,随机分成两组,对照组为自然愈合组,实验组为芦荟外涂组,实验组每日进行鲜芦荟凝胶对辐射伤口区的外涂,每日两次。辐射伤后6、10、18、24、34d各活杀大鼠10只,每组各5只。分别记录肉芽组织均数和创面愈合率。结果:实验组肉芽组织均数和创面愈合率较对照组高,两组间差异有显著性。结论:芦荟凝胶对放射性皮炎的愈合有促进作用。

【Abstract】 Objective:To observe effects of the aloe gel for the wound healing rate and the granulation tissue rate in healing of radioactive dermatitis vesicular reaction in rats. Methods: The rats models of 10% II radioactive dermatitis vesicular reaction on nude back were established. The rats were divided into 2 groups randomly: the normal healing group was the control group, and experimental group treated with aloe gel twice a day. At the 6th,10th,18th, 24th, 34th day after radiation, 5 rats in each group were killed, the wound healing rate and the granulation tissue rate were detected. Results: The wound healing rate and the granulation tissue rate in experimental group were significantly higher than that in control group. Conclusion: The aloe gel can promote the healing of radioactive dermatitis vesicular reaction.

【基金】 2001年陕西省医药管理局基金项目(No.816)
  • 【文献出处】 现代肿瘤医学 ,Journal of Modern Oncology , 编辑部邮箱 ,2006年09期
  • 【分类号】R818.7
  • 【被引频次】7
  • 【下载频次】193
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