【摘要】 目的了解太原市结核病医院结核菌耐药现状。方法采用回顾性调查的方法,收集近3年经过药敏测定的116例肺结核患者药敏结果。结果总耐药率79%,总耐多药率25%;初始耐药率68%,初始耐多药率12%;获得性耐药率91%,获得性耐多药率39%,耐多药率逐年增加。耐单药顺位由高到低依次为乙胺丁醇(EMB)、异烟肼(INH)、链霉素(SM)、利福平(RFP)、吡嗪酰胺(PZA)、对氨基水杨酸钠(PAS)。结论高耐药率尤其是高耐多药率是我院结核菌的耐药特点,也反映我省当前比较严峻的结核菌耐药形势。更多还原

【Abstract】 Objective To summarize current situation of tubercule bacillus′ drug-resistance in Taiyuan Tuberculosis Hospital.Methods Collected 116 samples of tuberculosis patients whose sensitivity against drugs was tested in the past 3 years.Results Rate of total drug-resistance was 79%,rate of total multidrug resistance was 25%,rate of initial drug resistance was 68%,rate of initial multidrug resistance was 12%,rate of acquired drug resistance was 91%,and rate of acquired multidrug resistance was 39%.The rate of multidrug resistance was increased year by year.Sequence of single drug resistance from the higher to the lower was EMB,INH,SM,RFP,PZA and PAS.Conclusion Higher rate of drug resistance,especially higher rate of multidrug resistance is the characteristic of tubercule bacillus drug-resistance in Taiyuan Tuberculosis Hospital.It shows the seriousness of tubercule bacillus drug resistance.更多还原