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角茴香有效部位的筛选

Selection of Effective parts in Fructus Illicii Veri

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【作者】 郭洁张喜德黄伟

【Author】 Guo Jie~1 Zhang Xide~1 Huang Wei~2(1.Shaanxi College of Traditional Chinese Medicine,Xianyang,Shaanxi 7120462.Master in Shaanxi College of Traditional Chinese Medicine,Xianyang,Shaanxi 712046)

【机构】 陕西中医学院陕西中医学院 陕西咸阳712046陕西咸阳712046硕士研究生陕西咸阳712046

【摘要】 目的筛选角茴香发挥保肝、镇痛、抗炎作用的有效部位。方法用系统溶剂分离法将角茴香分离成极性不同的组分,通过角茴香不同组分对硫代乙酰胺致肝损伤的保护作用、角茴香不同组分对热板法引起小鼠疼痛的影响以及角茴香不同组分对二甲苯所至小鼠耳肿胀的影响,筛选角茴香发挥保肝、镇痛以及抗炎作用的有效部位。结果角茴香正丁醇提取部位为角茴香发挥保肝作用的物质基础,氯仿提取物为角茴香发挥镇痛抗炎作用的有效部位。

【Abstract】 Objective To select the effective parts in Fructus Illcii Veri on protecting liver,releasing pain and anti-inflammation. Method Divided Fructus Illicii Veri into groups according to different polarities with system solution exclusion.Selected the effective parts in Fructus Illicii Veri on protecting liver,releasing pain and anti-inflammation by the protective effect of different groups on liver injury due to thioacetamide,effect of different groups on mice’s pain because of hot plate and effect of different groups on mice’s ear swelling owing to dimethyl benzene. Result The parts for extracting n-butanol in Fructus Illicii Veri was substances protecting the liver,while chloroform extract was the effective parts fot releasing pain and anti-inflammation.

【基金】 陕西省中医管理局资助项目1(2005058)
  • 【文献出处】 陕西中医学院学报 ,Journal of Shaanxi College of Traditional Chinese Medicine , 编辑部邮箱 ,2006年02期
  • 【分类号】R284
  • 【被引频次】13
  • 【下载频次】337
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