【摘要】 探索了磷酸四钙(C a4(PO4)2O,TTCP)的制备,并合成了磷酸钙骨水泥(CPC),对CPC固化时间、引起浸泡液pH值的变化、抗压强度、产物物相组成及微观结构进行了研究。结果表明:在真空条件下、1 500℃下煅烧6h可制得TTCP,并含有少量C aO。CPC初凝时间为4 m in、终凝时间为15 m in,浸泡1 d和7 d后的抗压强度分别为20 M Pa和35 M Pa,浸泡液的pH值在6.4~8.9之间变化,这些性能均符合临床用CPC的性能要求。CPC水化产物为片状或针状羟基磷灰石(C a5(PO4)3OH,HA),相互交错呈连续分布的网状结构,这种结构有利于材料强度的提高。实验研制的CPC材料可用于骨缺损的修复治疗。更多还原

【Abstract】 The preparation of tetracalcium phosphate（（Ca₄（PO₄）₂O,） TTCP）was studied.Then calcium phosphate cement（CPC）was prepared.The setting time,pH value,compressive strength,X-ray diffraction（XRD） and scanning electron microscope（SEM） analysis of CPC were studied.The results show that TTCP containing small amount of CaO can be successfully attained heated at（1 500） ℃ for 6 h in vacuum condition.The initial setting time and final setting time of CPC is 4 min and 15 min,respectively.Its compressive strength is 20 MPa after 1-day immersion and 35 MPa after 7-day immersion.The pH value of the solution changes between 6.4 and 8.9.These properties can satisfy the clinical requirements of CPC.The final product of CPC is flake-like or needle-like hydroxyapatite（（Ca₅（PO₄）₃OH,） HA）.The continuous network structure of HA appears in the microstructure,this leads to increase the strength of the material.This CPC can be used as bone substitute material.更多还原