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希尔伯特变换法分析心室颤动电压与电除颤结果的相关性研究

Hilbert Transform Analysis of the Relation between Ventricular Fibrillation Voltage and the Outcome of Defibrillation Shocks

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【作者】 王珂邓小燕郭然Abhijit PatwardhanFabio Leonelli

【Author】 Wang Ke~(1,2) Deng Xiaoyan~1 Guo Ran~2 Patwardhan Abhijit~3 Leonelli Fabio~31(Key Lab for Biomechanics & Tissue Engineering of Ministry of Education,College of Bioengineering,Chongqing University,Chongqing 400044,China)2(The First Affiliated Hospital of Dalian Medical University,Dalian 116011,China)3(Center for Biomedical Engineering & Division of Cardiology,University of Kentucky,Lexington,KY 40506-0070,USA)

【机构】 重庆大学生物工程学院生物力学与组织工程教育部重点实验室大连医科大学附属第一医院心内科Center for Biomedical Engineering & Division of Cardiology University of KentuckyLexingtonKY 40506-0070USACenter for Biomedical Engineering & Division of CardiologyUniversity of Kentucky重庆400044大连116011

【摘要】 探讨数字化的心电图(ECG)绝对心室颤动电压(AVFV)与心室电除颤结果之间的相关性。在11只成龄犬中按矢状方向(Y轴)、横向(X轴)和纵向(Z轴)连接电极建立正交ECG并安置经静脉双导管心脏电除颤系统;诱发室颤持续10 s,按选定的除颤成功率为50%的电量进行电除颤;使用希尔伯特(H ilbert)变换测定ECG包络电压。结果显示:在236个心室电除颤成功的试验(DF 1)和249个电除颤失败的试验(DF 2)两组中的AVFV包络电压无明显一致性的差别;DF 1组的移动平均电压并不大于DF 2组,其Z轴方向上电压反而小于DF 2组。研究表明:心室颤动期间ECG的AVFV与心室电除颤结果之间无很强的相关性。

【Abstract】 The objective of this study is to evaluate the correlation between the absolute ventricular fibrillation voltage(AVFV) computed from electrocardiogram(ECG) and the outcome of defibrillation shocks.Orthogonal ECG(sagittal,x;transverse,y;and longitudinal,z) was recorded from 11 dogs during 10 seconds of electrically induced ventricular fibrillation followed by defibrillation shocks with 50% probability of success.The transvenous two-leads defibrillation system was used to deliver defibrillation shocks.The envelope voltage was estimated by using the Hilbert transform.The comparison of the envelope voltages between 236 successful trials and 249 unsuccessful trials did not show any consistent and statistically significant differences.In contrast with the previously reported correlation,the moving average of AVFV was not higher in the successful trials.In the Z direction,the successful trials had lower voltage than did the unsuccessful trials(P<0.05).These results suggest that the absolute voltage of ECG during ventricular fibrillation is not robustly correlated with the outcome of defibrillation shocks.

  • 【文献出处】 生物医学工程学杂志 ,Journal of Biomedical Engineering , 编辑部邮箱 ,2006年03期
  • 【分类号】R541.75
  • 【被引频次】3
  • 【下载频次】71
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