【摘要】 为了研究中药配伍过程中是否发生化学反应,先从单味药材中提取不同的组分或大类化合物,然后对其进行配伍,用高效液相色谱法(HPLC)测定其在配伍前后的成分变化。实验采用HPLC对黄连生物碱与吴茱萸黄酮配伍后的各色谱峰进行检测和分析,结果表明黄连生物碱与吴茱萸黄酮配伍后色谱峰具有加和性,各成分的相对峰面积未见明显变化,且未见新的色谱峰产生,说明黄连生物碱与吴茱萸黄酮配伍后没有发生化学反应。更多还原

【Abstract】 In order to study the compatibility of Chinese herbal drugs,a method was proposed by investigating chemical reactions with combination of chemical constituents or major groups of chemical compounds of Chinese herbal drugs.The content variation of chemical constituents during combination of rhizoma coptidis alkaloids with fructus evodiae flavonoids was analyzed by high performance liquid chromatography(HPLC).The experimental results showed that only small changes of the relative peak areas of different chemical constituents were observed and no new peaks were detected.No chemical reactions were observed during the compatibility test of rhizoma coptidis alkaloids with fructus evodiae flavonoids.更多还原