节点文献
转金属硫蛋白基因平菇对初成年、衰老和铅中毒小鼠学习记忆能力的影响
Effects on Learning and Memorizing Abilities of Varied Model Mice Fed with Transgenic Metallothinoein Mushroom
【摘要】 本文研究了转金属硫蛋白基因平菇对不同模型小鼠学习记忆能力的影响。结果表明:在小鼠饲料中掺入1%转金属硫蛋白基因平菇干粉(相当于50~60kg体重的人每日摄食鲜菇1kg)可明显提高初成年小鼠和铅中毒小鼠的学习能力;增加剂量对成绩提高无进一步的作用。3.16%的掺入量对提高初成年小鼠的记忆能力有显著作用。但1%和3.16%两个剂量对D-半乳糖致衰老小鼠的学习记忆能力均未见有促进作用。
【Abstract】 Effects on learning and memorizing abilities of varied model mice fed with transgenic metallothinoein(MT)mushroom were studied in this paper.The results showed that the dried transgenic MT mushroom could significantly improve learning ability of early adulthood mice and lead poisoning mice when there was 1% MT mushroom in mixed feed(corresponding to doses of 1kg/d to human whose body weight is 50~60kg).No further improvement was found when MT mushroom dosage increased.The dosage of 3.16% MT mushroom could significantly improve the memorizing ability of early adulthood mice,but there was no effect on improvement of learning and memorizing ability to senile mice caused by injecting D-galactose under skin with both dosage of 1% and 3.16% MT mushroom.
【Key words】 metallothionein; transgenic; mushroom; mice; learning and memorizing ability;
- 【文献出处】 食品科学 ,Food Science , 编辑部邮箱 ,2006年08期
- 【分类号】R114
- 【被引频次】2
- 【下载频次】127