【摘要】 目的对γ射线照射后发生急性白血病的4例患者进行病因学判断。方法应用《放射性肿瘤诊断标准》(GBZ 97—2002)和美国电离辐射生物效应委员会第5号报告(BEIR V)的方法计算病因概率(PC)。结果根据上述两种方法,4例患者的PC值分别为98.9%vs 99.5%、98.5%vs 99.6%、81.6%vs 94.3%和91.1%vs 99.9%。结论4例PC值均≥50%,根据GBZ 97—2002,上述患者均可诊断为放射性肿瘤。对两种计算方法的差别进行了讨论。更多还原

【Abstract】 Objective To determine the causation for 4 cases of acute leukemia who were previously exposed to gamma-ray.Method The probability of causation(PC)was calculated with corresponding models described in Diagnostic criteria for radiogenic neoplasms(GBZ 97—2002)and Report V of Committee on the Biological Effects of Ionizing Radiations(BEIR V).Result According to the two models mentioned above,the PC in these four casaes were 98.9% vs 99.5%,98.5% vs 99.6%,81.6% vs 94.3% and 91.1% vs 99.9%,respectively.Conclusion Since the PC values in these four cases all exceeded 50% and well met the criteria of GBZ 97—2002,all the cases mentioned above could be diagnosed as radiogenic neoplasms.Moreover,the difference between two methods for PC calculation was also briefly discussed in the paper.更多还原