【摘要】 目的评价18F-脱氧葡萄糖(FDG)PET-CT定性及半定量显像技术在直肠癌术后局部复发诊断中的临床价值。方法对20例临床可疑直肠癌术后局部复发的患者行全身18F-FDG PET-CT显像,将显像结果与病理组织学及临床随访结果对比。结果病理组织学及临床随访证实,局部复发15例。采用定性方法诊断直肠癌术后局部复发的灵敏性和特异性分别为100%、60%。采用半定量法显示恶性肿瘤的标准摄取值(SUV,范围为2.7~17.2,平均9.9)明显高于良性病变者(SUV为1.3~4.0,平均2.6),诊断直肠癌术后局部复发的灵敏性和特异性分别为100%、80%。结论全身18F-FDG PET-CT显像有利于直肠癌术后局部复发的定性及定位诊断;半定量方法较定性法更具有特异性。更多还原

【Abstract】 [Objective] To determine the value of ¹⁸ F-FDG PET-CT qualitative and semi-quantitative imaging technique on diagnosis of local recurrence in postoperative rectal tumor.[Methods] Twenty patients with suspected recurrent colorectal carcinoma underwent whole-body FDG PET.PET results were compared with the final histopathological and clinical follow-up findings.[Results] Recurrent malignancy was confirmed in 15 patients by histopathological examination.Benign lesions were confirmed in five patients by surgery or clinical follow up.Qualitative analysis of the FDG PET data had a sensitivity of 100%（15/15） for recurrent disease and a specificity of 60%（3/5）.SUV were significantly higher in malignant lesions（range =2.7-17.2,mean=（9.9）） than in benign ones（range=1.3-4.0,mean=2.6;P=0.002）.[Conclusion] Whole-body FDG PET/CT is accurate in the staging of patients with suspected recurrent rectal carcinoma.Quantitative analysis is more specificity than visual analysis for recurrent disease.更多还原