【摘要】 目的:探讨射频消融治疗慢性肥厚性鼻炎所致鼻塞的效果及对鼻黏膜功能的影响。方法:采用射频消融术治疗慢性肥厚性鼻炎60例的双侧下鼻甲,术前及术后3个月应用视觉模拟评分表(visual ana-logue scale,VAS)评价鼻塞的主观感觉;应用糖精试验法测定术前及术后3个月的鼻腔黏膜纤毛输送率(mu-cociliary transport rate,MTR)。结果:术前鼻塞VAS评分左侧为(68.7±9.6)%,右侧为(72.5±10.2)%;术后3个月左侧为(35.0±9.0)%,右侧为(40.3±10.6)%,与术前相比,差异均有统计学意义(P<0.01)。随访3个月,双侧下鼻甲与鼻中隔的最小距离从术前小于0.2 cm增加到术后大于0.3 cm。术前鼻黏膜纤毛MTR为(7.64±1.56)mm/min,术后3个月鼻黏膜纤毛MTR为(6.89±2.01)mm/min,与术前比较差异无统计学意义(P>0.05)。结论:射频消融术是治疗慢性肥厚性鼻炎所致鼻塞的较好方法,对鼻黏膜纤毛无明显影响,未破坏鼻黏膜纤毛的正常生理功能。更多还原

【Abstract】 Objective: To assess the efficacy of bipolar radiofrequency ablation on nasal obstruction and cilia of nasal mucosal in patients with inferior tubinate hypertrophy.Methods: Sixty patients were enrolled in this study,and bipolar radiofrequency ablation was used on inferior turbinate.Visual analogue scale(VAS) was used to investigate the pre-and post-operative 3-month nasal obstruction,and sacchariu technique was used to test the mean nasal mucociliary transport rate(MTR).Results: Mean obstruction(VAS) improved from 72.5%±10.2% to 40.3%±10.6%(right side),and from 68.7%±9.6% to 35.0%±9.2%(left side);MTR was from preoperative(7.64±1.56)mm/min to postoperative 3-month(6.89±2.01)mm/min.Conclusion: Radiofrequency for submucosal tissue ablation in treatment of the hypertrophied inferior turbinate is effctive for relieving the nasal obstruction,and it has no obvious side effect on nasal mucosa function.更多还原