【摘要】 目的通过对甘羟铝片溶出度进行方法学研究,提高甘羟铝片的质量可控性,确保药品的临床疗效。方法试验采用稀盐酸做为溶出介质,依法确证辅料的干扰程度及含量测定方法的可行性。结果及结论该溶出度研究方法是比较切实可行的,为质量标准再评价工作提供了一些具有科学价值的理论数据。更多还原

【Abstract】 OBJECTIVE Through dissolution behavior study of Dihydroxyaluminium Aminoacetate to enhance its quality controllability,and guarantee clinical curative effect.METHODS Used diluted hydrochloric acid as dissolvent,to ensure the disturbance degree of accessories and proof the feasibility of testing method .RESULTS and CONCLUSION The new trial technique was quite practical and feasible,and can be provide some gross data for appraising quality specification.更多还原