【摘要】 目的:探讨影响正常压力脑积水分流手术效果的因素。方法:回顾性分析31例正常压力脑积水(NPH)患者临床症状、病程、年龄、腰椎穿刺放液试验等因素对脑室-腹腔分流术的影响及预后效果。结果:本组在术前腰穿实验后1周内症状有所改善17例,无手术死亡病例。依照疗效判定标准,本组总有效率70.9%。步态不稳术后有效率72.7%,智力障碍术后有效率44.4%,尿失禁术后有效率40%。结论:以步态不稳为主要症状,病程短、年轻,腰穿试验阳性者分流手术效果好,以痴呆和尿失禁为主要症状者分流效果差。更多还原

【Abstract】 Objective: To evaluate the factors acted on the shunting normal pressure hydrocephalus(NPH).Methods: The efficacy of shunting was retrospectively analyzed according to 31 NPH patients′ symptoms,medical history,age and test of draining cerebrospinal fluid(CSF) with lumbar puncture.Results: Seventeen patients got better after test of draining CSF with lumbar puncture,no one died.The total response rate was 70.9%,and the response rate of patients with gait disturbance was 72.7%,of patients with amentia was 44.4%,of patients with urine incontinence was 40%.Conclusion: Young patients with gait disturbance and short course of disease have good or excellent response to surgery,whereas patients with amentia or urine incontinence have poor response to surgery.更多还原