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注射型丙烯酸树脂骨水泥生物学安全性评价研究
Biological Safety Evaluation of Injectable Acrylic Bone Cement
【摘要】 按照国家标准GB/T16175-1996、GB/T14233.2-1993、GB/T16886-1997的有关规定,对注射型丙烯酸树脂骨水泥进行生物学安全性评价研究。结果表明,注射型丙烯酸树脂骨水泥各项生物学指标均合格。其各项生物学指标均符合国家标准GB/T16175-1996、GB/T14233.2-1993、GB/T16886-1997的要求,具有良好的生物相容性。
【Abstract】 To evaluate the biological safety of the injectable acrylic bone cement.8 experiments were conducted to evaluate the injectable acrylic bone cement according to national standard(GB/T16175-1996,GB/T14233.2-1993、GB/T16886-1997).The biological evaluation of the injectable acrylic bone cement was satisfied with the requirement of the National Standard(GB/T16175-1996,GB/T14233.2-1993、GB/T16886-1997).The experiment results demonstrate that the injectable acrylic bone cement has ideal hemo-compatibility,no Cytotoxicity,systemic toxicity(acute toxicity),sensitization,intracutaneous reactivity,genotoxicity.The conclusion is that the biocompatibility of injectable acrylic bone cement is safety.
【Key words】 Injectable acrylic; Bone cement; L-929cell; Implanted into muscle; Biological evaluation;
- 【文献出处】 生物医学工程研究 ,Journal of Biomedical Engineering Research , 编辑部邮箱 ,2006年01期
- 【分类号】R318.08
- 【被引频次】4
- 【下载频次】176