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放射治疗结合热疗治疗宫颈癌的疗效观察

The Effect of Radiotherapy Combined with Hyperthermia for Cervix Carcinoma

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【作者】 沈湘余忠华梁荣刘付冬

【Author】 SHEN Xiang, YU Zhong-hua, LIANG Rong, et al (Department of Radiation Oncology,Affiliated Hospital of Guangdong Medical College ,Zhangjiang 524001, China)

【机构】 广东医学院附属医院肿瘤放疗科广东医学院附属医院肿瘤放疗科 广东 湛江 524001广东 湛江 524001

【摘要】 目的:观察放射治疗加热疗治疗宫颈癌的临床效果。方法:将66例经病理确诊的宫颈癌患者随机分为两组:放射治疗+热疗组(热放组)33例和单纯放射治疗组(单放组)33例。两组的放射治疗方法一样:全盆照射+盆腔四野照射+腔内后装放疗。热放组采用了射频深部热疗和微波腔内热疗,热疗每周1次至2次,直至放疗结束。每次热疗均在放疗后30分钟内开始。结果:热放组和单放组的局部控制率(CR)分别为84.8%和 60.6%,有显著性差异(P<0.05)。1年、2年的生存率两组无显著差异(P>0.05),但3年生存率分别为84.8%和 63.6%,有着显著性差异(P<0.05)。结论:放射治疗结合热疗可提高宫颈癌患者的局部控制率和生存率。

【Abstract】 Objective: To determine the efficacy of radiotherapy combined with hyperthermia for cervix carcinoma. Methods: 66 cases of cervix carcinoma diagnosed by pathology were divided randomly into two groups; 33 patients treated with radiotherapy plus hyperthermia (H + R group) ; 33 patients treated with radiotherapy alone (R group). Radiotherapies of both groups were alike: pelvic external irradiation plus intracavitary brachytherapy. H + R group was treated with hypothermia, which was given 30 minutes after radiotherapy, once or twice per week, until radiotherapy was over. Results: The local control rates of H + R group and R group were 84. 8% and 60.6% ( P < 0.05) respectively. The 3-year survival rates of H + R group and R group were 84. 8% and 63.6% (P < 0.05) respectively, though there was no statistical significance in the 1-year and 2-year survival rates. Conclusion: Radiotherapy combined with hyperthermia is instrumental in raising the local control rate and survival rate for the patients with cervix carcinoma.

【关键词】 宫颈癌放射治疗热疗预后
【Key words】 Cervix NeoplasmRadiotherapyHyperthenniaPrognosis
  • 【文献出处】 四川肿瘤防治 ,Sichuan Journal of Cancer Control , 编辑部邮箱 ,2006年02期
  • 【分类号】R737.33
  • 【被引频次】4
  • 【下载频次】99
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