【摘要】 目的观察急诊经皮冠状动脉介入术后血栓前状态与术后冠脉并发症的关系。方法选择2003年至2005年期间50例因急性心肌梗死(AMI)在佛山市第二人民医院行急诊经皮冠状动脉介入术(PCI)的患者,于急诊PCI术后24h内抽取静脉血测定血栓前状态指标D-D和PAT,所有患者观察28d,根据术后有无严重冠脉并发症将患者分为两组,并发症组(A组)和非并发症组(B组),回顾性分析A、B两组的血栓前状态指标D-D和PAT,评价急诊PCI术后血栓前状态指标D-D和PAT与术后冠脉并发症的关系。结果所有50例AMI患者的血栓前状态指标D-D和PAT均较正常值升高,其中A组术后24h内D-D为(1.8±0.4)ng/L,B组D-D为(0.8±0.2)ng/L,B组明显低于A组(P<0.001);A组术后24h内PAT为(44±10)s,B组PAT为(16±5)s,B组明显低于A组(P<0.01)。结论急诊PCI术后血栓前状态指标D-D和PAT较正常值升高,D-D和PAT升高的水平是术后严重冠脉并发症的预测指标,积极降低D-D和PAT水平有可能明显降低术后严重冠脉并发症的发生率。更多还原

【Abstract】 Objective To determine the relationship between coronary complications and thrombus status after primary PCI. Methods During 2003 to 2005, 50 patients with AMI and receiving primary PCI were selected in this study. D-D and PAT were measured at 24 hours after primary PCI. All patients were observed for 28 days and were divided into two groups, namely group A (with complication) and group B (without complication). D-D and PAT were analysised retrospectively. The relationship between complications and anterior thrombus status after primary PCI were evaluated. Results D-D and PAT of all patients stepped-up. D-D in the group A and group B patients was (1.8±0.4) ng/L and (0.8±0.2) ng/l, respectively (P<0.001). PAT in the group A and group B patients was (44±10)s and (16±5)s, respectively (P<0.01). Conclusion D-D and PAT of all patients stepped-up after primary PCI. Levels of D-D and PAT can be used as markers to predict the incidence of coronary complication. Reducton of D-D and PAT may decrease the incidence of coronary complication.更多还原