【摘要】 目的评价瑞芬太尼复合异丙酚静脉麻醉用于B超引导下经阴道穿刺取卵术的安全性和有效性。方法ASAⅠ～Ⅱ级不孕症患者80例,随机分为瑞芬太尼复合异丙酚组(A组)和单用异丙酚组(B组),每组各40例。A组瑞芬太尼1.0μg·kg-1持续静注60s,随后静注异丙酚2mg·kg-1,B组静注异丙酚2mg·kg-1诱导,术中维持每次追加异丙酚0.5～1.0mg·kg-1。观察术中血流动力学的变化,注射痛发生情况,记录异丙酚总用量、术毕睁眼时间和不良反应。结果两组患者诱导后SBP、DBP有不同程度下降(P<0.01),组间无显著性差异。A组患者心率诱导后5min与诱导前相比明显下降(P<0.01)。A组注射痛发生率、异丙酚总用药量明显少于B组(P<0.01),术毕呼之睁眼时间明显短于B组(P<0.05)。结论瑞芬太尼复合异丙酚静脉麻醉用于B超引导下经阴道穿剌取卵术是安全可行的,具有镇痛强、苏醒较快、显著减少异丙酚用量等优点,值得临床推广应用。更多还原

【Abstract】 Objective To evaluate the effects and the safety of remifentanil with propofol anesthesia for ultrasound-guided oocyte pickup by vagina puncturing. Methods 80 ASAⅠ～Ⅱ patients undergoing ultrasound-guided oocyte pickup by vagina puncturing were randomly divided into two groups, each of 40 patients: group A and B. Group A was anesthetized with remifentanil 1.0 μg·kg-1 and propofol 2 mg·kg-1, while group B was anesthetized with propofol 2 mg·kg-1, and was maintained with propofol 0.5～1.0 mg·kg-1. The following parameters were recorded and compared between the two groups:①Hemodynamic changes during anesthesia; ②Pains of intravenous injection; ③The duration of eye opening at request after termination of anesthesia; ④The quantity of propofol used; ⑤The side-effects after operation. Results During anesthesia SBP and DBP were significantly low in the two groups(P<0.01). The incidence of pains of intravenous injection was significantly lower in group A than that in group B(P<0.01). The quantity of propofol used was less in group A than that in group B(P<0.01). The duration of eye opening at request was significantly lower in group A than that in group B(P<0.01). Conclusion Remifentanil with propofol anesthesia has better effect than high dose of propofol alone when used for ultrasound-guided oocyte pickup by vagina puncturing.更多还原