【摘要】 目的采用热球凝切(thermal balloon ablation,TBA)子宫内膜对月经过多的病人进行研究,观察长期疗效及生活质量的改变。方法采用TB型子宫内膜治疗仪对70例月经过多病人进行TBA治疗,术后连续随访24个月,以电话或面见的方式,随访临床症状及生活质量状况,并作相应的统计学处理。结果术后6、 12、18、24个月治疗有效率分别为95．71％、94．28％、87．14％、84．29％。,再次手术有5例,占7．14％。术前与术后 24个月时相比,月经期从(8．8±2．2)d／周期缩减至(4．1±1．3)d／周期,P<0．0001;月经量从(11．4±2．6)片／d减至 (4．8±1．5)片／d,P<0．001。血红蛋白从(82．75±12．40)g／L,上升为(110．30±1．00)g/L,P<0．0001;生活质量 (SRHMS)量表健康评定总分从(166．50±10．11)分上升到(357．33±32．16)分,P<0．0001。结论 TBA治疗月经过多,可改善患者临床症状,同时提升生活质量。更多还原

【Abstract】 Objective The purpose of this study was to assess long-term efficacy and the changes of quality of life after thermal balloon ablation for abnormal uterine bleeding. Methods Seventy women who underwent thermal balloon ablation with thermal balloon endometrial ablation system in our institution initially had their charts reviewed for demographics, procedure data, clinical history, and follow-up 24 months. Thereafter, a telephone or an interview was conducted to assess post procedural menstrual pattern, quality of life. Data were compared with the use of appropriate tests for categoric or continuous variables and logistic regression. Results The cure rates at 6、12、18 and 24 months were 95.71%,94.28%,87.14% and 84.29%, respectively. 5 cases were repeated the operation once,with a percentage of 7.14%. The bleeding period per cycle(8.8 vs 2.2 days,P<0.0001) and the use of pads per day (11.4 vs 4.8 pads/ d,P<0.001)were reduced. The hemoglobin levels ( 82.75±12.40)g/L vs (110.30±1.00)g/L differed significantly before and after 24 months TBA, (P<0.0001). And there was also an improvement in self-reported quality of life scores (SRHMS) after treatment (166.50±10.11)vs (357.33±32.16),P<0.0001. Conclusion The thermal balloon ablation is a safe and efficient method to treat abnormal uterine bleeding. It reduces the menstrual flow and improves the quality of life.更多还原