【摘要】 目的观察高血压病人脑核磁共振成像(MRI)的改变以及认知功能变化,以提高对脑卒中和痴呆防治的认识。方法选取190例的人群分为观察组和对照组,其中观察组95例为高血压病人,对照组95例为非高血压病人。观察两组人群的脑MRI的改变以及认知功能变化。结果观察组脑白质疏松症、腔隙性梗死的现患率明显高于对照组,观察组认知功能改变也明显高于对照组。结论高血压病是脑白质疏松症、腔隙性梗死及认知功能改变等亚临床脑损害的独立危险因素,血压水平与亚临床脑损害呈一定的剂量-反应关系。更多还原

【Abstract】 Objective To identify early pre-clinical damage of the brain with patients suffer from HBP and understand the way of combating dementia and stroke of brain by studying change of the brain on MRI and cognition on patients with HBP. Methods There were 95 patients with HBP in the experimental group and 95 patients without HBP as the control.Observe the changes of the brain on MRI and cognition of all the patients. Results There were much more patients with leukoaraiosis and lacunar infarct on the brain in the experimental group compared with the control,also with the change of cognition. Conclusion HBP was the independent factor of leukoaraiosis and lacunar infarct on the brain and the obstacles of cognition.There were some dose and response relations between the level of blood pressure and the pre-clinical damage.更多还原