【摘要】 目的:探讨大肠癌患者医院感染危险因素,加强医院感染的防治。方法:采用回顾性调查方法对我院普外科2004年1月~2005年12月实施根治性手术的大肠癌患者的医院感染情况进行流行病学调查分析。结果:68例大肠癌患者医院感染率22·10%,涉及医院感染的病死率26·67%;感染部位以呼吸道和造瘘口为主,各占感染人数的40·00%和20·00%;病原菌以白色念珠菌和大肠埃希菌为主,分别占44·44%和20·00%。感染因素与患者年龄、住院天数、接受化疗、应用激素及多种抗生素使用有关,差异有统计学意义,P<0·01。结论:恶性肿瘤患者并发医院感染严重影响预后,也是导致患者非肿瘤死亡的主要因素,减少或消除口咽部和胃肠道病原菌的定植吸入、减少切口的细菌污染、合理应用化疗、激素和抗菌药物是降低大肠癌患者医院感染的重要环节。更多还原

【Abstract】 OBJECTIVE:To discuss the dangerous factors of the large intestine patients’ nosocomial infection as well as its clinical control measures. METHODS: The retrospective investigation was used in the large intestine cancer patients’ nosocomial infection situation which in January, 2004-2005 years in December implemented the radical cure surgery in the general surgery in our hospital to carry on the epidemiology analysis. RESULTS: 68 cases of large intestine cancer patients’ nosocomial infection rate was 22.10%, involving the nosocomial infection the cases fatality (mortality) rate was 26.67%. The infection places which were respiratory tract and made the fistula mouth were 40.00% and 20.00%, respectively. The pathogen germs were Candida albicans and large intestine Egypt primarily, which account for 44.44% and 20.00% separately. The infection factor was related to the patient age or the days in hospital, the application of the chemotherapy, hormone and many kinds of antibiotic, which were significantly different (P<0.01). CONCLUSION: Malignant tumor patient with nosocomial infection serious influence prognosis. It is also causes the patient of non-tumor death the primary factor. It is the nosocomial infection important link to reduce or eliminate the planting inspiration and bacterium pollution. We must reasonable use chemotherapy, hormone and antibiotics.更多还原