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胃癌术前的选择性动脉介入治疗的研究
Selective intra-arterial chemoembolization of preoperative gastric cancer
【摘要】 目的评估胃癌术前介入治疗的临床疗效和病理变化。方法总结61例胃癌患者术前接受选择性动脉内插管化疗和动脉内栓塞治疗的结果。其中包括手术所见、病理组织学改变和临床疗效。结果61例胃癌的组织病理学改变总有效率为86.88%,有效者中,轻度有效29例(47.54%),中度以上有效24例(39.34%)。生存率比较,介入治疗组(平均52.30月)和单纯手术组(平均38.50月)的差异具有统计学意义(P<0.05)。结论胃癌术前行介入治疗,创伤轻微,疗效显著,应作为术前的一项常规治疗。
【Abstract】 Objective To evaluate the effects of preoperative transcatheter arterial chemotherapy (TAC) and transcatheter arterial embolization (TAE) in gastric cancer patients. Methods Sixty one cases of gastric cancer were treated by selective intra-arterial perfusion of chemoembolization and transcatheter arterial embolization before operation. Clinical manifestations, findings in operation, pathological changes and clinical effects were retrospectively reviewed. Results The overall histopathologically response rate was 86.88%. Slight efficiency was in 29 patients (47.54%), moderate in 24 patients (39.34%). The average survival duration of the transcatheter arterial chemotherapy was 52.30 months and operation group was 38.50 months,there was significant difference between two groups(P<0.05). Conclusion TAC and TAE before operation are safe, effective and worthy in gastric cancer patients.
【Key words】 gastric cancer; transcatheter arterial chemotherapy; embolization; histopathology;
- 【文献出处】 全科医学临床与教育 ,Clinical Education of General Practice , 编辑部邮箱 ,2006年02期
- 【分类号】R735.2
- 【被引频次】3
- 【下载频次】67