【摘要】 目的：探讨难治性癫癎手术治疗的临床疗效及脑电图(EEG)变化。方法：对43例难治性癫癎患者手术前、术中、术后分别进行常规脑电图(EEG)、长程录像脑电图(VEEG)监测及皮层电图(ECoG)监测,并定期随访,统计手术前后癫癎发作情况及进行脑电活动对比分析。结果：长程VEEG癎样波的检出率及定位率均显著高于EEG；术后EEG异常率显著下降(P＜0．01)；癫癎发作消失或发作频率显著减少。结论：EEG监测下手术是治疗难治性癫癎的有效方法。更多还原

【Abstract】 Objective:To study the effect of operation on treating intractable epilepsy patients and electrophysiologic changes.Methods:Electroencephalogram(EEG)and long term video Electroencepha- logram(VEEG)were recorded before and after operation in 42 patients with intractable epilepsy.Cortical Electroencephalogram(ECoG)recording technique was used in operation procedure.The seizure of epi- lepsy patients and their brain electric activities were analyzed before and after operation.Results:The de- tectability rate of epileptic waves were higher in VEEG than that in EEG;The abnormality rate of Elec- troencephalograms after operation were lower(P＜0.01);The seizure frequency was diminished or sei- zure free after operation.Conclusions:Surgery treatment is an efficient method to cure patients with in- tractable epilepsy under the monitoring of brain electric activity.更多还原