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隐睾患儿血清FSH、LH、T水平及其临床意义

The clinical significance of serum hormones(FSH、LH、T)level in children cryptorchidism

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【作者】 张建星; 李笃妙; 傅冷西; 林俊山; 宋非无;

【Author】 Zhang Jian xing Li Dumiao Fu Lengxi Lin Junshan Song Feiwu Department of Pediatric Surgery and Central Laboratory,the First Affiliated Hospital,Fujian Medical University,Fuzhou 350005,China

【机构】 福建医科大学附属第一医院小儿外科; 福建医科大学附属第一医院中心实验室; 福建医科大学附属第一医院小儿外科 福州350005; 福州350005;

【摘要】 目的研究隐睾患儿血中促卵泡激素(FSH)、促黄体激素(LID和睾酮(T)激素水平变化,探讨其临床意义及在隐睾症发病中的作用。方法应用化学发光免疫技术检测42例隐睾症和23例斜疝(对照组)患儿血清FSH、LH、T水平。结果单侧隐睾症组和斜疝组之间血清FSH、LH和T水平无显著性差异(P>0.05);(2)双侧隐睾组血清FSH水平高于斜疝组,差别有统计学意义(P<0.05);单侧隐睾症组血清FSH高于斜疝组,低于双侧隐睾症组,差别无统计学意义(P>0.05)。结论(1)血清中性激素LH和T水平的变化在隐睾发生中并不起主要作用;(2)血清FSH水平的升高可能反映睾丸功能损害严重程度。

【Abstract】 Objective To investigate the level of follicle-stimulating hormone (FSH),luteotropic hormone (LH), testosterone (T) in children cryptorchidism and to explore the clinical singnificance and the role of mechanism in cryptorchidism. Methods Chemiluminescence immunoassay was used to examine the serum levels of FSH,LH and T in 42 cases of cryptorchidism and 23 cases of inguinal hernia as the contrast.Results (1) The levels of serum LH and T in bilateral cryptorchidism,unilateral cryptorchidism and hernia were not different (P>0.05).(2) The serum FSH level in bilateral cryptorchidism was significantly higher than that of hernia (P<0.05).The serum FSH level in unilateral cryptorchidism was higher than that of hernia and lower than that of bilateral cryptorchidism,but there were no statistical differences with them (P>0.05).Conclusion (1) The serum LH and T levels may play a negligible role during the testicular descent in cryptorchidism.(2) The increase of serum FSH is possible positive correlated to the functional lesion of testes.

【关键词】 隐睾痖; 激素类; 儿童;
【Key words】 cryptorchidism; hormones; child;
【基金】 福建省教委资助项目(编号K20056)
  • 【文献出处】 中国男科学杂志 ,Chinese Journal of Andrology , 编辑部邮箱 ,2006年06期
  • 【分类号】R726.92
  • 【被引频次】3
  • 【下载频次】86
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