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帕金森病患者的交感神经皮肤电反应的初步探讨

A Primary Study of Sympathetic Skin Response in Parkinson’s Disease Patients

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【作者】 黄慧王晓明赵小琼胡建秀马英

【Author】 HUANG Hui,WANG Xiao-ming,ZHAO Xiao-qiong,HU Jian-xiu,MA Ying (Department of Neurology,the Affiliated Hospital of North Sichuan Medical College,Nanchong,Sichuan 637000,China)

【机构】 川北医学院附院神经内科川北医学院附院神经内科 四川南充637000四川南充637000

【摘要】 目的探讨交感神经皮肤电反应(SSR)在判断帕金森病(PD)患者自主神经功能障碍中的价值。方法采用肌电/诱发电位仪对PD患者和健康人分别进行SSR检测并对比分析。结果PD患者SSR潜伏期上肢为(1.89±0.40)s,下肢为(2.19±0.56)s;波幅上肢为(0.68±0.50)mV,下肢为(0.49±0.58)mV,分别较对照组(1.48±0.12)s、(1.93±0.19)s、(2.09±0.20)mV、(1.25±0.38)mV明显延长及降低,两组比较有显著性差异(p值均<0.05)。结论SSR对判断PD患者的自主神经功能障碍具有一定临床意义。

【Abstract】 Objective To study the value of sympathetic skin response in assessing the autonomic nerve disorder in PD patients.Methods Using electromyography/evoked potential equipment,sympathetic skin response of PD patients and healthy people were detected and the data were compared.ResultsThe mean latent period of upper limbs in PD patients was(1.89±0.40)s,and the lower(2.19±0.56)s,obviously longer than that of the control group which were(1.48±0.12)s and(1.93±0.19)s respectively;the mean amplitude in upper limbs was(0.68±0.50)mV,and the lower (0.49±0.58)mV,obviously decreased than that of the control group which were(2.09±0.20)mV and(1.25±0.38)mV respectively.Significance was found between the PD patients and the control group(p<0.05).ConclusionClinical value of sympathetic skin response was found in assessing the autonomic nerve disorder in PD patients.

【基金】 四川省医学重点学科建设项目(2002川卫138号)
  • 【文献出处】 川北医学院学报 ,Journal of North Sichuan Medical College , 编辑部邮箱 ,2006年03期
  • 【分类号】R742.5
  • 【被引频次】3
  • 【下载频次】78
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