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鼻咽癌生物治疗途径的探讨

Study on Biotherapy For Nasopharyngea Carcinoma

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【作者】 王薇陈海燕诸小侬

【Author】 WANG Wei~1,CHEN Hai-yan~1,ZHU Xiao-nong~2(1.Department of Otolaryngology,The Affiliatnd Hospital ofInner Mongolia Medical College,Huhhot 010050 China;2.Beijing Institute of Otolaryngology,Beijing 100005 China)

【机构】 内蒙古医学院附属医院耳鼻咽喉科北京市耳鼻咽喉研究所 内蒙古呼和浩特010050内蒙古呼和浩特010050北京100005

【摘要】 目的:探讨鼻咽癌生物治疗途径与疗效的关系。方法:两组鼻咽癌患者分别进行IL-2局部和全身免疫治疗,用免疫组化方法检测T细胞、嗜酸性粒细胞的表达及胶原纤维数量的变化。结果:两组中T细胞、嗜酸性粒细胞及胶原纤维数量有显著差异(P<0.05)。结论:鼻咽癌生物治疗以局部应用为主。

【Abstract】 Objective:To investigate the relation between methods on biotherapy for nasopharyngeal carcinoma and their curative effect.Methods:The patients with nasopharyngeal carcinoma in boty groups were treated with local IL-2 and systemic IL-2.The expression of T cells and eosinophill and the change in numbers of collagen fiber were detected by immunohistochemistry.Results:There was significant difference in the expression of T cells and eosinophill and the number of collagen fiber between two groups(P<0.05).Conclusion:The local biotherapy is the key in treatment of nasopharyngeal carcinoma.

  • 【文献出处】 内蒙古医学杂志 ,Inner Mongolia Medical Journal , 编辑部邮箱 ,2006年08期
  • 【分类号】R739.63
  • 【下载频次】61
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