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育子丸治疗精核蛋白异常男性不育30例临床分析

Clinical Analysis of Yuziwan in the Treatment of 30 Sterile Men with Abnormal Protamine

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【作者】 王旭初; 李海松; 潘天明;

【Author】 WANG Xu-chu ~(1),LI Hai-song ~(2),PAN Tian-ming ~(3)Center of Reproductive Medicine,Cangzhou Hospital of Integrated TMC and Western Medicine,Cangzhou,Hebei 061001,China;2.Center of Reproduction,Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine,Beijing 100700,China;3.Center of Reproduction,Peking University Third Hospital,Beijing 100083,China

【机构】 沧州中西医结合医院生殖医学中心; 北京中医药大学附属东直门医院男科中心; 北京大学第三医院生殖中心 河北沧州061001; 北京100700; 北京100083;

【摘要】 目的:研究育子丸临床治疗精核蛋白异常男性不育的方法及效果。方法:观察30例男性不育患者用育子丸治疗前后精核蛋白、精液参数、性激素的变化情况。结果:育子丸治疗1个疗程(3个月)后,治愈9例,显效15例,无效6例。治疗后,组蛋白/精核蛋白的比例[(0.72±0.32)]较治疗前[(1.34±0.52)]下降,差异有显著性(P<0.01);精液质量较治疗前明显改善(P<0.05);LH、T水平较治疗前显著提高(P<0.01)。治疗后中医症候改善25例。结论:育子丸治疗精核蛋白异常的男性不育具有良好疗效。

【Abstract】 Objective:To study the clinical application and effects of Yuziwan in the treatment of male sterility patient with abnormal protamine.Methods: The changes of protamine,semen and sex hormones of 30 male sterility patients treated by Yuziwan were observed before and after the treatment.Results: After a 3-month course of treatment,9 cases were cured,15 obviouosly improved and 6 failed to respond.The ratio of histone to protamine was decreased from((1.34)±(0.52)) before the treatment to((0.72)±(0.32)) after it,with significant difference(P<(0.01)),the semen quality obviously improved(P<(0.05)),and the LH and T levels markedly raised(P<(0.01)).Yuziwan evidently improved the abnormal protamine,sperm quality and endocrine function of the sterility patients.Conclusion: Yuziwan has good curative effect on male sterility.

【关键词】 男性不育; 育子丸; 精核蛋白; 精子;
【Key words】 male infertility; Yuziwan; protamine; sperm;
【基金】 河北省卫生厅基金资助(05069)
  • 【文献出处】 中华男科学杂志 ,National Journal of Andrology , 编辑部邮箱 ,2006年11期
  • 【分类号】R256.56
  • 【被引频次】5
  • 【下载频次】94
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