【摘要】 目的:探讨引起圆头精子症的原因。方法:对1例圆头精子症患者进行精液常规分析、精子DNA特殊染色及外周血淋巴细胞染色体等检查。结果:圆头精子症患者的精子顶体缺如,顶体酶活性很低,Y染色体短臂多一条带。结论:圆头精子症患者的精子顶体缺如、顶体酶活性降低以及染色体异常可能是导致不育的一个主要原因。更多还原

【Abstract】 Objective: To investigate the etiologic factors of globozoospermia.Methods: Routine semen analysis,sperm DNA special staining and chromosomal karyotype detection of peripherical blood lymphocytes were performed in a globozoospermia patient.Results: Round-headed spermatozoa were lack of acrosome and the acrosin activity was low.Meanwhile,there was an additional band located in the Y chromosomal short arm.Conclusion: Lack of acrosome,low acrosin activity and abnormality of chromosome may be the main reasons for globozoospermia. Natl J Androl,2006,12(6):537-539更多还原