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影响睾丸引带发育的内分泌因素研究进展
Advances in the Endocrine Factors Affecting the Development of Gubernaculum Testis
【摘要】 睾丸引带与睾丸下降关系密切,它的分化发育和多种因素有关,特别是雄激素、降钙素基因相关肽、胰岛素样因子3、苗勒管抑制物质、表皮生长因子以及环境雌激素(EEs)等,其中降钙素基因相关肽、胰岛素样因子3和EEs对生殖系统的影响是目前研究的热点。从影响睾丸引带发育的角度探讨EEs对睾丸及生殖发育的影响很有意义。
【Abstract】 The testicular gubernaculum plays an important role in testicular descent and development.Its differentiation and development are affected by many factors.Androgens,calcitonin gene-related peptide(CGRP),insulin-like factor 3(INSL3),Müllerian inhibiting substance(MIS),epidermal growth factor(EGF) and environmental estrogens(EEs) are involved in gubernacular development.The effect of CGRP,INSL3 and especially EEs on genital system has been attracked more attention.
【关键词】 睾丸引带;
雄激素;
降钙素基因相关肽;
胰岛素样因子3;
环境雌激素;
【Key words】 gubernaculum; androgen; calcitonin gene-related peptide; insulin-like factor 3; environmental estrogens;
【Key words】 gubernaculum; androgen; calcitonin gene-related peptide; insulin-like factor 3; environmental estrogens;
【基金】 广东省自然科学基金(010438);广东省科技攻关项目基金(C31302)
- 【文献出处】 中华男科学杂志 ,National Journal of Andrology , 编辑部邮箱 ,2006年05期
- 【分类号】R33
- 【被引频次】3
- 【下载频次】183