【摘要】 采用高效液相色谱法同时测定丹参酮胶囊中隐丹参酮和丹参酮ⅡA含量,建立丹参酮胶囊质量控制体系。采用C18柱分离测定;甲醇:水(80∶20)为流动相,检测波长:270nm;流速:1.0m l/m in。结果:隐丹参酮和丹参酮ⅡA分别在0.20~160μg(r>0.999 9)、0.21~1.68μg(r>0.999 8)质量范围内线性关系良好;回收率在98.7%~103.0%之间。更多还原

【Abstract】 To establish a method for determination of Cryptotanshinone and Tanshinone ⅡA in Danshentongiaonang by HPLC,the chromatographic method was carried out on C₁₈ column using CH₃OH-H₂O（80∶20）as the mobile phase.The detection wavelength was 270nm and flow rate was 1.0 ml/min.Results:The linear ranges for Cryptotanshinone and Tanshinone ⅡA were 0.20～（1.60μg）（r>0.999 9）and 0.21～1.68μg（r>0.999 8）respectively.Conclusion:The method is simple,sensitive and rapid with satisfactory recoveries and reproducibilities.更多还原