【摘要】 目的研究不同给药方法在胃镜检查术中的镇静作用及对血流动力学的影响。方法30例胃镜检查患者随机分为三组,A组(异丙酚2mg/kg),B组(咪达唑仑0.08mg/kg),C组(咪达唑仑0.04mg/kg+异丙酚1~2mg/kg),每组10例,观察术中心率(HR)、平均动脉血压(MAP)、脉搏血氧饱和度(SpO2)及镇静分级、苏醒时间、术中不适、记忆缺失及自我感觉等情况。结果A组MAP、SpO2下降与B、C两组比较差异有统计学意义(P<0.05),C组MAP虽有下降趋势,但无统计学意义。镇静分级、苏醒时间、术中不适、记忆缺失及自我感觉A、C两组优于B组(P<0.05)。结论异丙酚复合咪达唑仑用于胃镜检查术是安全有效的。更多还原

【Abstract】 Objective To study the effect on sedation,respiration and circulation of propofol and midazolam used by three different ways in fibrogastroscopy.Methods Thirty patients undergoing gastroscopy were randomly divided into three groups: group A（propofol group）,group B（midazolam group）and group C（propofol+ midazolam group）.Heart rate（HR）,mean arterial pressure（MAP） grade of sedation,time for recovery of consciousness,discomfort,amnesia and self-felling were recorded.Results MAP and SpO₂ were significantly lower in group A than those in both group B and C（P<0.05）.MAP was significantly lower in group C than that in group B（P<0.05）.Grade of sedation,time for recovery of consciousness,amnesia,discomfort and self-felling were all well in both group A and group C,and both were better than in group B（（P<）0.05）.Conclusion Propofol and midazolam are safe and effective in gastroscopy.更多还原