【摘要】 目的了解2型糖尿病住院患者各种慢性并发症的流行病学现状,为临床防治提供依据。方法入选1000例2型糖尿病患者,其中男性621人,女性379人,分别占62．1％和37．9％;年龄33-81岁．平均52．28±11．34岁,病程0-32年,平均7．67±3．16年。调查内容包括患者的基本情况、相关病史资料、代谢指标及各种糖尿病慢性并发症的诊断情况。结果慢性并发症发生率:视网膜病变41．4％,白内障14．8％,高血压29．6％,肾脏病变27．2％,冠心病19．2％,下肢血管病变8．4％,脑血管病变12．1％．干、湿性坏疽1．8％。周围神经病变74．8％,植物神经病变52．8％。各种慢性并发症发生率除白内障、下肢血管病变、脑血管病变、肾脏病变及坏疽在各年龄组间无显著性差异外,其他并发症随年龄增加而增加(P<0．01);白内障、冠心病、脑血管病变及坏疽除在各病程组间无显著性差异外,其他并发症随病程增加而增加(P<0．01)。结论各种慢性并发症发生率随年龄、病程的增长呈上升趋势,此趋势在年龄60岁以上、病程在15年后尤其明显;年龄、病程、高血压、高血糖、血脂紊乱、糖基化血红蛋白是糖尿病慢性并发症发生的危险因素,严格控制这些危险因素是预防和延缓慢性并发症发生发展的重要措施。更多还原

【Abstract】 Objective To study the epidemiological status of the inpatients with type 2 diabetic chronic complications in Gansu Province and to provide some evidence for further prevent and treatment. Methods A total of 1000 cases, 621 men(62.1%) and 379 women(37.9%), with type 2 diabetes were investigated. Their age was 33-81 years with average of 52.28±11.34 years and diabetes duration was 0-32 years with average of 7.67±3.16 years. The basic condition of patients, related medical history data, metabolic index, diagnosis and treatment of all kinds of diabetic chronic complications were investigated. Results The incidence of the chronic complications: retinopathy disease 41.4%, cataract(14.8%), hypertension 29.6%, clinical diabetic nephropathy 27.2%, coronary heart disease(CHD) 19.2%, peripheral vascular disease(PVD) 8.4%, cerebrovascular disease(CVD) 12.1%, mummification necrosis and wet gangrene(1.8%), peripheral neuropathy(PNP) 74.8%, autonomic nerve disease 52.8%, respectively. There were significant differences among patients younger than 40 years old and patients younger than 50 years old but older than 40 years and patients younger than 60 years old but older than 50 years in above incidences(P < 0.01) except incidences of cataract, PVD, CVD, PNP and wet gangrene, and the complications increased as age increased. Complications increased as course of disease increased(P < 0.01) except in cataract, CHD, CVD and wet gangrene. Conclusion This survey manifested that the incidences of chronic complications increased as age and duration of disease increased, especially in patients older than 60 years, and the duration of disease longer than 15 years. Age, duration of disease, hypertension, high blood sugar, blood lipid disturbance and gly-cosylated hemoglobin are risk factors of diabetes chronic complications. It is important to prevent and delay the progress of diabetes chronic complications by controlling the above factors.更多还原