【摘要】 目的:探讨定量指标血流平均密度(MFD)在评价肝肿瘤超声造影前后血供情况的临床应用价值。方法:造影前对35个肝肿瘤病灶(原发性肝癌11个,转移性肝癌9个,血管瘤15个)行能量多普勒成像(CPA),计测病灶内MFD,经肘静脉注射造影剂SonoVue,对病灶行超声造影反向脉冲谐波(PIH)检查,计测造影后病灶内MFD,并分别与造影前对比、统计分析。结果:各组造影前与造影后MFD比较差异有统计学意义(P<0.05),造影后原发性肝癌组MFD(0.303±0.179),明显高于血管瘤组(0.093±0.064),两组间比较差异有统计学意义(P<0.05)。造影后转移性肝癌组分别与原发性肝癌组和血管瘤组比较,差异均无统计学意义(P>0.05)。结论:超声造影能提高不同性质肝肿瘤的血流信号,血流定量指标MFD能对肝癌与肝血管瘤的鉴别诊断提供有价值的信息。更多还原

【Abstract】 Objective: To explore the clinical application of quantitative index-MFD(mean flow density) before and after contrast-enhanced ultrasound(CEUS) in evaluating the blood supply of hepatic tumor. Methods: Thirty-five hepatic solid lesions, 11 cases of hepatocellular carcinomas(HCC), 9 cases of metastatic liver tumors(MLT), 15 cases of hepatic hemangiomas(HCH), were examined with color power angiography(CPA) before enhanced ultrasonography, then they were examined with pulse-inversion harmonic(PIH) ultrasonographic imaging after an intravenous administration of SonoVue. MFD were calculated and analysed before and after enhanced ultrasonography respectively. Results: There were significant difference of MFD before and after enhanced ultrasonography in each group(P<0.05). The MFD of HCC(0.303±0.179) were obviously higher than HCH(0.093±0.064) in enhanced ultrasonography(P<0.05). There was no obvious difference between MLT and the other two groups separately. Conclusion: CEUS can markedly improve the blood flow signals of hepatic tumor and MFD can provide an important information for differential diagnosis between HCC and HCH after CEUS.更多还原