【摘要】 目的探讨胃肠功能衰竭新生儿血清二胺氧化酶(DAO)和D-乳酸含量变化特点及其临床意义。方法19例胃肠功能衰竭新生儿为病例组,79例健康新生儿为对照组,测量两组新生儿血清DAO、D-乳酸含量。结果对照组血清DAO含量为(8.851±3.424)U/ml,血D-乳酸含量为(0.918±0.715)μg/ml。病例组血清DAO含量为(11.610±3.909)U/ml,D-乳酸含量为(1.859±0.972)μg/ml;病例组血清DAO、D-乳酸水平显著高于对照组(P<0.05,P<0.01)。不同疾病严重程度、不同胎龄、不同日龄患儿血清DAO、D-乳酸含量比较无显著性差异(P>0.05)。结论血清DAO和D-乳酸含量测定可作为新生儿胃肠功能衰竭早期诊断的敏感指标。更多还原

【Abstract】 Objective To investigate the levels of serum diamine oxidase(DAO) and D-lactate in neonates with gastrointestinal failure and its clinical significance.Methods Ninety-eight newborn infants were divided into two groups,nineteen neonates with gastrointestinal failure were observed as cases group and seventy-nine healthy newborn were as control,the levels of serum DAO and D-lactate in two groups were detected.Results The levels of serum DAO and D-lactate in cases group and control group were(11.610±3.909)?U/ml,(1.859±0.972)?μg/ml and(8.851±3.424)?U/ml,(0.918±0.715)?μg/ml respectively.The levels of serum DAO and D-lactate in cases group were significantly higher than those in control group.The levels of serum DAO and D-lactate in cases group were not increased in proportion with the severity of disease.There were no significant differences in the levels of serum DAO and D-lactate between premature infants and mature ones,and also between neonates younger than 3 days and older than 3 days.Conclusion Serum DAO and D-lactate may be early markers for gastrointestinal failure in neonates.更多还原