【摘要】 目的总结我院呼吸机相关肺炎(VAP)的发生情况、病原学特征及预后因素。方法回顾分析我院1998年1月~2004年12月间164例机械通气患儿的临床资料,并对VAP预后因素进行分析。结果VAP发生率25·2%。VAP患儿插管次数、机械通气时间以及机械通气并发症发生率显著高于对照组。主要病原体为假单胞菌。VAP患儿脏器功能衰竭的数目及心肾功能衰竭发生率显著高于对照组。结论插管次数和机械通气时间影响VAP的发生,重要脏器的功能影响VAP的预后。应有针对性地对VAP患儿进行监控,并根据病原学结果合理用药。更多还原

【Abstract】 Objective To evaluate the prevalence,etiological feature and prognostic factors of ventilator-associated pneumonia (VAP) in our hospital.Methods Clinical data of 164 ventilated patients from January 1998 to December 2004 were analyzed retrospectively and the prognostic factors were evaluated statistically.Results The incidence of VAP was 25.5% among the 164 ventilated cases.As compared with the control,patients with VAP had higher intubation frequencies,longer ventilating duration and higher ventilator-related complication rate.Pseudomon aseruginosa was the predominant pathogenic bacteria of VAP.Additionally,patient with VAP had higher incidence in MODS,heart failure and renal failure in contrast to the control.Conclusion The intubation frequency and ventilating duration contributed to the pathogenesis of VAP.The function of vital organs significantly influenced the prognosis of patients with VAP.The patients of VAP should be monitored closely and treated according to the etiological findings.更多还原