【摘要】 [目的]果蝇伴性隐性致死试验观察食用油烟雾(FEO)和食用油加热剩油(CEO)的致突变作用。[方法]分别用FEO(110、320、960μg/ml)和CEO(416、833、1667μg/ml)的3个不同浓度喂饲果蝇对其细胞的遗传毒性进行研究。[结果]320μg/ml浓度组的FEO第Ⅰ、Ⅱ、Ⅲ窝致突变率分别达到0.257%、0.530%和0.506%(P<0.001);110μg/ml浓度组的第Ⅰ窝和960μg/ml浓度组的第Ⅰ、Ⅱ窝与对照组相比差异有显著性(P<0.001)。所有CEO浓度组的伴性隐性致死试验结果都呈阳性(P<0.001),但未见剂量-反应关系。[结论]FEO和CEO对雄性黑腹果蝇具有较高的毒性作用。更多还原

【Abstract】 [Objective] To observe the effects of the fume of edible cooking oil (FEO) and the cooked edible oil (CEO) to induce mutation using a Sex-Linked Recessive Lethal Test (SLRL test) in Drosophila melanogaster.[ Methods] Drosophila was fed with the CEO and FEO at three different concentrations as following: 416 μg/ml, 833 μg/ml and 1667 μg/ml for CEO; 110 μg/ml, 320 μg/ml and 960 μg/ml for FEO, respectively. [ Results] The mutagene rates of FEO at 320 μg/ml concentration from first brood to third brood were 0.257%, 0.530% and 0.506%, respectively, and there are same results that of the first brood at 110 μg/ml and the third brood at 320 μg/ml or 960 μg/ml compared with negative control (P < 0.001). The results of CEO in all groups treated produced a positive response in SLRL test (P < 0.001) but there is no dose-response relationship among different groups.[ Conclusion] Both of FEO and CEO have highly toxic effect on the male Drosophila melanogaster.更多还原