【摘要】 目的:利用高频超声研究颈、股动脉粥样硬化超声标识与冠状动脉粥样硬化的关系。方法:对91例冠状动脉造影受检者术前行双侧颈、股动脉超声检查,测定血管后壁内膜中层厚度(IMT)和斑块厚度,记录斑块数目,半定量估计斑块的严重程度。根据冠状动脉造影结果分为正常组和冠心病组。冠心病组分别按血管狭窄≥50%所累及主要病变血管支数分:单支病变、双支病变、3支病变,其中左主干累及定为双支病变。结果:随着冠状动脉病变程度的增加,颈、股动脉IMT值均增加,冠心病组与正常组比较差异有统计学意义(P<0.05);颈、股动脉斑块分级与冠状动脉病变血管支数分级间显著相关(P<0.05);股动脉斑块对冠心病预测的准确度(69.23%)高于颈动脉斑块(56.04%)。结论:颈、股动脉粥样硬化超声标识似用以预测冠心病的严重程度。更多还原

【Abstract】 Objective:To investigate the association between ultrasonic signals of carotid and femoral arteriosclerosis and coronary artery disease (CAD). Methed:The intima-media thickness (IMT) and plaque thickness of carotid and femoral arteries were measured in 91 patients before undergoing coronary arteriography (CAG). The numbers of plaque were recorded and the grades were semi-quantified. These patients were divided into normal group and CAD group.The extent of CAD was coded as 0, 1, 2, or 3 according to the number of major coronary vessels with luminal stenosis ≥50%. Left main Stenosis ≥50% was scored as 2-vessel disease. Result:The IMT progressively increased with the extent of CAD,The IMT of CAD group was obviously higher than that of normal group (P<0.05); there was significant correlation between the plaque grades and the extent of CAD (P<0.05); the predictive accuracy to CAD by detecting the femoral artery plaque was higher than the carotid plaque (69.23% vs 56.04%). Conclusion:Ultrasonic signals of carotid and femoral arteriosclerosis have great value in predicting the extent of CAD.更多还原